A 2-month-old male infant, the second twin of a twin pregnancy, born at 36 + 5 weeks, was admitted with progressive ...

Medicine is replete with preadministration safety rituals that seemed self-evident until they were formally studied. Routine ...

Introduction Acetazolamide improves sleep apnoea in people living at low altitude and newcomers ascending to high altitude.

Systemic sclerosis (SSc) is a systemic autoimmune disease characterised by immune dysregulation and multiorgan fibrosis. 1 ...

A 65-year-old male, who does not smoke, with a history of right lower lobectomy for carcinoid tumour 15 years prior, was referred for persistent, unexplained cough over 12 months. This was ...

Rationale/Objectives Despite plausible pathophysiological mechanisms, research is needed to confirm the relationship between sleep, circadian rhythm and delirium in patients admitted to the intensive ...

Objective: To determine the risk factors for and outcomes associated with the rapid decline in lung function in a cohort of elderly US adults. Methods: Data from 4923 adult participants aged 65 years ...

2 Department of Medicine, Division of Pulmonary, Critical Care and Sleep Disorders Medicine, University of Louisville, Kentucky, USA 3 Department of Medicine, Johns Hopkins University School of ...

Introduction The evidence that teaching self-management techniques to children and young people with asthma in schools is effective has not, to date, been the subject of systematic review. Methods We ...

Introduction Blood eosinophil count (BEC) is a recognized biomarker predicting response to inhaled corticosteroids, and possibly biologics, in chronic obstructive pulmonary disease (COPD). However, ...

Background Obstructive sleep apnoea (OSA) is a heterogeneous disorder, and improved understanding of physiologic phenotypes and their clinical implications is needed. We aimed to determine whether ...

Background: There is a growing recognition that genetic predisposition contributes to the development of fibrotic interstitial lung disease. Adult onset monogenic disease is most commonly due to ...