When reading articles about genetic testing, terms like PCR, Sanger sequencing, NGS, and digital PCR often appear.While all ...
A research team led by Professor Kim Tae-kyung at POSTECH, in collaboration with Qurient, has identified the mechanism by which the ...
A new iScience study shows that the error-prone polymerase Pol ι is induced in BRCA2-deficient mammary epithelial cells, ...
New research shows that damaged extrachromosomal DNA is trapped in transcriptionally silent micronuclei, impairing cancer ...
Artificial intelligence has taken another leap forward in the realm of genomics. In a remarkable breakthrough, Claude, a general-purpose AI model, uncovered a novel DNA editing mechanism called ART ...
A record player-like microscope and computer simulations solve a longtime mystery, showing that metal ions bridge DNA strands that would normally repel.
Newswise — Scientists have long been fascinated by two promising classes of antibiotics that disable RNA polymerase (RNAP). They knew that these drugs could grind gene expression to a halt in several ...
Translesion synthesis (TLS) is a DNA damage tolerance pathway that enables cells to replicate across damaged DNA, thereby promoting cell survival under genotoxic stress, however, contributing to ...
Roughly 20 million people receive a cancer diagnosis each year, and an estimated 1 in 5 people will receive a cancer diagnosis in their lifetime. Cancer cells arise from damage to the cell's ...
Nucleoside analogues, such as ganciclovir, a leading drug for preventing and treating human cytomegalovirus, are a critical defense against viral diseases. However, antiviral resistance often results ...
PARP inhibitors reshaped oncology when they first reached patients some 10 years ago, but they represent just one entry point into a much larger and more intricate biological network.
High-pathogenicity influenza viruses have not only been devastating the planet’s wild and domestic bird populations, but they also represent a persistent threat of initiating a fatal human influenza ...