Drinking coffee with certain prescription or over-the-counter medications can reduce their effectiveness or cause dangerous ...

Abstract: Predicting drug-drug interaction (DDI) plays a crucial role in drug recommendation and discovery. However, wet lab methods are prohibitively expensive and time-consuming due to drug ...

Introduction: Various drugs can markedly disrupt gut microbiota, resulting in a reduction of beneficial microbial populations and precipitating a range of negative clinical consequences. Traditional ...

Background: Low-dose methotrexate (MTX) is a standard treatment for ectopic pregnancy. While generally safe, it can rarely cause life-threatening hematologic toxicity. The mechanisms underlying these ...

Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt Natural Products Discovery Core, Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, United ...

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Abstract: Adverse drug-drug interactions (DDIs) pose potential risks in polypharmacy due to unknown physicochemical incompatibilities between co-administered drugs. Recent studies have utilized ...

Xerostomia is defined as the perception of dry mouth, and dysgeusia, as a change in taste. Both are common complaints in the elderly, especially among those making use of polypharmacy drug ...

Many of us line up our pills on the table and swallow them one after another—painkiller, vitamin, maybe even a leftover antibiotic—without a second thought. But when medicines mingle inside the body, ...