Acrivon Advances ACR-7280, an Optimized, AP3-Enabled, Potential First-in-Class, Oral CDK11 Inhibitor Toward IND Filing in First Half of 2027

ACR-7280 demonstrated complete tumor regression in aggressive AML xenograft modelsPrioritized among multiple AP3-discovered, highly selective ...
BIOENGINEER

Phosphorylated M18BP1 unlocks human condensin II on DNA

Cryo-electron microscopy and single-molecule experiments show how phosphorylated M18BP1 relieves condensin II autoinhibition, enabling stable DNA binding and compaction in vitro.
El Heraldo de San Luis Potosí

Mecanismos de dolor crónico, específicos de la mujer

(Venkataraman A et al. Science 2026; 69-74 10.1126/science.aeh4468) Las mujeres padecen trastornos de dolor funcional más ...