The Buffalo Bills are now slightly favored over the Kansas City Chiefs to finish as the No. 1 seed in the AFC.

During the San Francisco 49ers 35-10 loss to the Buffalo Bills on Sunday night, superstar running back Christian McCaffrey suffered a PCL injury in his right knee in what is feared to be season-ending ...

The Buffalo Bills (10-2) are on the road in Week 14 to face the LA Rams (6-6) at SoFi Stadium on Sunday afternoon. Kickoff is ...

ABC NewsLake effect snow is slamming the Great Lakes, with seven states from Wisconsin to New York under snow alerts on ...

Mike Florio and Chris Simms unpack the Bills dominant victory over the 49ers in the snow in Week 13, and why Buffalo is "no ...

Buffalo Bills quarterback Josh Allen enhanced his MVP credentials with a win over the San Francisco 49ers.

Back in April, Nix was famously the sixth quarterback to come off of the board, following Caleb Williams at pick one, Jayden ...

In an otherwise boring game against San Francisco -- the result of the game was never in question -- Bills quarterback Josh ...

Whether it's Duff’s wings or The Anchor Bar, where legend has it the Buffalo wing was born, Americans' obsession with the ...

While the Detroit Lions didn't play Sunday, they did remain atop the NFC standings and still share the best record in the ...

The Buffalo Bills easily got past the San Francisco 49ers 35-10 on a snowy Sunday Night Football matchup. Here are winners ...

Pittsburgh is in command of the AFC North after Russell Wilson's big day against Cincinnati. Detroit, Philadelphia and ...