The announcement Sunday that former President Joe Biden was diagnosed with advanced prostate cancer has some people wondering how the disease could have been missed.

Doctors not involved in Biden's care said his diagnoses shows the challenges of screening for prostate cancer.

Biden’s diagnosis comes at a difficult time for the former president, as scrutiny grows over his decision to run for a second term last year.

Biden, even after he has exited political life and as he faces a serious cancer diagnosis, remains a factor in the conversation about his party's political future.

“Every day is a nightmare, and evening is even worse,” he said. Dilbert the comic strip first appeared in 1989, poking fun at office culture. It ran for decades in numerous newspapers but disappeared following racist remarks by Adams. The Associated Press contributed to this report.

The U.S. Bureau of Prisons is failing to routinely screen older inmates for colorectal cancer, and has in some cases failed to follow up with proper medical care after inmates tested positive in cancer screening,

About 1 in 8 men will be diagnosed with prostate cancer during their lifetime, and it is the second-leading cause of cancer death in American men, according to the American Cancer Society. What do you want to know about prostate cancer risks,

Pfizer jumps into cancer-treatment race with a $6 billion licensing deal with a China-based company, six months after Merck’s move for a lot less money.