Islamist-led rebels are pressing a major offensive in northern Syria in which they seized the second city Aleppo from the government for the first time since civil war erupted in 2011.

Follow NBC News for live updates on the latest coverage from the Middle East, where Syria is battling rebels and Israel and Hezbollah have traded fire.

The US and NATO-backed war for regime change in Syria, launched in 2011, has been revived. Turkey, Syria’s northern neighbour ...

Last week, apparently catching the world by surprise, Hayat Tahrir al-Sham (HTS) rebels launched a surprise offensive against ...

The consequences of recent events in the Middle East and their impact on the military balance. Thomas L. Friedman shares his ...

The Syrian civil war has reignited after four years of docility, with five main players deciding the course of events.

Insurgents have breached Syria’s second-largest city, Aleppo, and were clashing with government forces on the city's western edge on Friday, according to a Syria war monitor and fighters ...

Syria’s long civil war has reclaimed global attention after insurgents seized most of its largest city and dozens of nearby towns and villages.

The latest US sanctions are part of an effort to disrupt Iran’s use of oil revenue to finance its nuclear programme.

Iran and Russia, both stretched by conflicts of their own, have experienced setbacks in Syria after a rebel offensive in the ...

Israel’s defense minister says that if the shaky ceasefire with Hezbollah collapses, Israel will widen its strikes and target ...

Iraq will not act as a mere spectator in Syria where it believes groups and sects are victims of ethnic cleansing, Iraq's ...