It’s been a trying season for the 49ers. After going through multiple unthinkable experiences and the unavoidable injury bug, ...

Kyle Shanahan shouldered the blame for the San Francisco 49ers' defensive and overall team struggles this season.

It’s been a rough day – and a rough season - for 49ers fans. Many are depressed over a brutal loss Monday night in Buffalo ...

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

Head Coach Jim Harbaugh meets with the media to discuss the Week 13 victory over the Atlanta Falcons. Outside linebacker Joey ...

Meanwhile, the 5-6 49ers are dealing with massive injury struggles. All-Pro left tackle Trent Williams, Defensive Player of ...

Purdy is officially listed as questionable for the game, though coach Kyle Shanahan said the plan is for him to start on ...

Defensively, two of the 49ers’ best players this season are out and will not travel as defensive end Nick Bosa (obliques, ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

Head coach Kyle Shanahan shared the final injury report on QB Brock Purdy, DL Nick Bosa and others and discussed the team's ...

First comes Brock Purdy, the team's star quarterback, who missed Week 12 with a right shoulder. While Purdy is still ...

The San Francisco 49ers are preparing for their Week 13 contest against the Buffalo Bills on Sunday at Highmark Stadium in ...