A change in one gene can disrupt thousands of others in HD. A study in pigs suggests an explanation: expanded huntingtin ...

Its speech measures reflected clinical scores and HD-related changes over time, suggesting it could be used as a remote ...

In plain language. Written by scientists. Scientists discovered that a specific type of brain cell becomes unusually quiet in Huntington’s disease. By restoring the activity of these cells in mice, ...

Most of us know what it’s like to have something stuck in our minds. A catchy song. A favourite YouTube video you watch again. A conversation that keeps circling in your mind. Usually, our brains move ...

Unique research highlights an overlooked mental health disparity among Indigenous North American people with HD – and the need for care grounded in trust, community partnership, and cultural ...

September was another busy month for Huntington’s disease (HD) research. Scientists explored new ways to track changes in the brain, took a huge-data approach to understanding the DNA repeats at the ...

The CAG repeat that causes HD has a tendency to grow with age. New research on over 900,000 people uncovers parallel patterns and finds CAG growth can happen in many other parts of the genome. But ...

Gene silencing drug injected into spinal fluid in ALS patients proves safe. Good news for similar planned HD trials.

In plain language. Written by scientists. A new study from researchers at Thomas Jefferson University delves into the details of how genetic modifiers of Huntington’s disease work. Both PTC ...

In plain language. Written by scientists. September brought progress across the HD research landscape. From brain waves and visual thinking to DNA repeats, nutrition, inclusive care, new technologies, ...