Starter Christian McCaffrey (knee) is amid his second IR stint, and his backup, Jordan Mason, is also on IR with a high-ankle ...

Breaking down all of the good and some of the bad from the 49ers’ much-needed blowout win over the Bears in Week 14.

With Christian McCaffrey and Jordan Mason on injured reserve, Guerendo made his first NFL start against the Bears. If he ...

With Christian McCaffrey and Jordan Mason on injured reserve, Guerendo made his first NFL start against the Bears. If he ...

San Francisco needed to play together, and they finally did against Chicago, setting up a must-win matchup against the Rams.

The San Francisco 49ers are reportedly expected to lean on rookie running back Isaac Guerendo for the remainder of the 2024 ...

The San Francisco 49ers’ exceedingly deep backfield thinned out rapidly when running backs Christian McCaffrey and Jordan ...

Both of these teams are nowhere near where they'd like to be this season, but with one finding a rejuvenated energy to ...

The Los Angeles Rams divisional rival, the San Francisco 49ers are having a disappointing season. The 49ers have dealt with ...

The San Francisco 49ers are facing another setback as defensive lineman Nick Bosa is officially out for Sunday's game.

Already missing five starters during the blowout loss to the Bills, San Francisco lost star running back Christian McCaffrey ...

The San Francisco 49ers have officially released updates on offensive tackle Trent Williams and defensive lineman Nick Bosa.