A modeling study expanded benzene and phenol oxidation chemistry and reduced it to 30 reactions for regional air-quality models while retaining the pathways that dominate chamber-derived aerosol mass.
A new review argues that benzothiazole derivatives, acting through DHFR inhibition and heme detoxification, could yield ...
Simcere Pharmaceutical Co. Ltd. has divulged bicyclic compounds acting as lysosomal acid glucosylceramidase (GBA; β-glucocerebrosidase) positive allosteric modulators reported to be useful for the ...
Sometimes films come out at a time that lines up eerily well with real life. As Americans debate the ethics of the nearly ubiquitous Flock cameras that are being placed in neighborhoods all throughout ...
Flat aromatic rings such as benzene have dominated the pharmaceutical landscape for more than 200 years. But chemists increasingly want to replace them with rigid, 3D molecular structures that can ...
One of the upsides to keeping your money in a bank account is the chance to earn compound interest — you earn interest on both the funds you deposit in an account and on the interest that money earns.
To be listed as a hazardous constituent under RCRA, scientific studies must show that the chemical has toxic, carcinogenic, mutagenic, or teratogenic effects on humans or other life forms. EPA ...
When Aisha Patterson first moved into a family compound in Oklahoma in 2023, the primary goal was to become more self-sufficient. With 20 acres of land for three households — one for Patterson plus ...
Bicycle Therapeutics focuses on novel conjugated targeted therapies for cancer, with promising early results but no clear evidence of superior efficacy yet. Their lead compound, zelenectide pevedotin, ...
Bifloranes, also known as serrulatanes, feature a distinct 6,6-bicyclic framework and a prenyl side chain, showcasing a wide range of biological activities such as anti-inflammatory, antimalarial, and ...
Provided herein are novel bicyclic heterocyclic compounds as CD73 inhibitors, pharmaceutical compositions, use of such compounds in treating cancer, and processes for preparing such compounds. The ...