本研究针对单细胞RNA测序(scRNA-seq)数据中普遍存在的伪重复偏差问题,系统评估了包括DESeq2、MAST、DREAM、scVI等7种差异表达分析方法在嵌套数据结构中的性能。通过多场景模拟实验和真实数据集 ...
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