Injuries and missed opportunities have defined the San Francisco 49ers' 2024 season. Can they overcome setbacks and make a ...

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been ...

San Francisco 49ers quarterback Brock Purdy feels sorry for the brutal injury suffered by Christian McCaffrey.

With a 5-7 record, quarterback Brock Purdy delivered a clear and passionate message to his teammates: the time for excuses is ...

Daily Fantasy millionaire Mike McClure shares his top NFL DFS picks for Buffalo Bills vs. San Francisco 49ers on SNF ...

The San Francisco 49ers are in dire straights after a blowout loss to the Buffalo Bills, and QB Brock Purdy knows it.

Kirk Cousins threw four interceptions and tossed the Atlanta Falcons’ playoff plans into disarray. Brock Purdy couldn’t ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

Lake-effect snow has been hitting Buffalo throughout the holiday weekend with is expected to continue off and on through ...

The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFC West. Here are their grades for this per ...

The weather outside was frightful at Highmark Stadium in Orchard Park, New York on Sunday night, but the way the San ...

The Bills are coming off a bye week and riding a six-game winning streak behind MVP favorite Josh Allen, most recently ...