T cell-based immunotherapies, including CAR-T cell therapies, have significantly advanced treatment options for lymphomas ...

Galapagos' CAR-T therapy GLPG5101 shows promise but faces challenges with limited data, cash reserves, and competition in the ...

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders ...

This study evaluated the efficacy of elranatamab (Elrexfio, Pfizer), which targets B-cell maturation antigen (BCMA) on ...

I, a protein platform for reprogramming immune responses. A better understanding of its structure may help optimize designs for the platform, which can be used to develop cancer treatments by either ...

Trial reveals no survival benefit from autologous stem cell transplant for mantle cell lymphoma patients with undetectable ...

Nemtabrutinib is a small molecule commercialized by Merck, with a leading Phase III program in Relapsed Chronic Lymphocytic Leukemia (CLL);Refractory Chronic Lymphocytic Leukemia (CLL).

diffuse large B-cell lymphoma, multiple myeloma, and follicular lymphoma. Intense global research is now exploring the clinical potential of CAR T-cell therapies beyond blood cancers, with therapies ...

In a meta-analysis, second-generation BTK inhibitors were linked to a significantly low incidence of atrial fibrillation, ...

A stem cell transplant added to Rituxan did not improve survival for MRD-negative MCL patients in their first remission ...

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Late-breaking research reveals there is no benefit from high-dose chemotherapy followed by autologous stem cell transplant (ASCT) for patients with mantle cell lymphoma (MCL) in remission following ...