The 49ers — who were already without Trent Williams, Nick Bosa and Deommodore Lenoir — saw Christian McCaffrey leave their ...

The San Francisco 49ers are reportedly expected to lean on rookie running back Isaac Guerendo for the remainder of the 2024 ...

San Francisco 49ers running back Christian McCaffrey left Sunday night's contest versus the Buffalo Bills with what the team ...

Trevor Lawrence, Christian McCaffrey and Taysom Hill were among key players injured in Week 13 of the NFL season.

The 49ers star running back was ruled out of Sunday Night Football after suffering a knee injury in the first half against ...

McCaffrey's old backfield mate discussed the trials and tribulations of a season-ending injury on his podcast.

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

The 49ers running back, the reigning NFL offensive player of the year, is facing a six-week recovery for a knee injury.

Christian McCaffrey suffered a PCL injury in the 49ers' Week 13 loss to the Bills. He addressed the injury on social media ...

Copyright 2024 The Associated Press. All Rights Reserved. San Francisco 49ers running back Christian McCaffrey (23) runs ...

The San Francisco 49ers running back injured the PCL in his knee, an MRI confirmed Monday. San Francisco plans to place McCaffrey on injured reserve. He is expected to miss six weeks. Head coach Kyle ...

Star running back Christian McCaffrey will miss the remainder of the regular season with a PCL injury sustained in the San ...