is a global, peer-reviewed, open access lupus journal from LFA, publishing papers on all aspects of lupus and related diseases.
Background SLE is a complex autoimmune condition requiring evaluation across disease activity, permanent damage and ...
Objective Systemic lupus erythematosus Prospective Observational Cohort Study (SPOCS) was a prospective observational study ...
Sjögren’s disease (SjD) is a chronic, systemic autoimmune disease characterized by exocrinopathy, extraglandular inflammation, and marked B-cell activation. Dryness, fatigue, pain, systemic organ ...
Objective Neuropsychiatric complications of systemic lupus erythematosus (SLE) lack relevant biological indicators that can be dynamically monitored. This study aims to break the technical barriers of ...
Objective To explore clinical outcomes associated with belimumab use in patients with SLE-associated pulmonary arterial hypertension (SLE-PAH). Methods We performed an ambispective cohort study of 10 ...
Objective To determine the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of subcutaneously administered mosunetuzumab, a CD20xCD3 T-cell-engaging bispecific antibody, in ...
Objective To examine B cell-activating factor (BAFF) and type I interferon (IFN) activity at the transcriptional and protein levels in blood and placental tissue in SLE compared with healthy ...
Objectives Neutrophil extracellular traps (NETs) are the autoantigenic drivers of autoimmunity in systemic lupus erythematosus (SLE). Their persistence is driven by excessive NET formation and ...
Objective To systematically identify herbal supplements with immunostimulatory properties that may trigger or exacerbate autoimmune skin diseases. Methods We conducted a systematic scoping review in ...
22 Historical aspects of B-cell depletion in SLE (8 October, 2025) ...
Haematologic involvement in patients with systemic lupus erythematosus (SLE) is very common. The principal cytopenias in lupus result in anaemia, white cell deficits and thrombocytopenia. Anaemia may ...
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