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Limited evidence exists on the prognostic role of continuing medical therapy in patients with heart failure (HF) and an ejection fraction (EF) that has improved over time. This study assessed rates of ...

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The decline in cardiovascular mortality achieved by the end of the 20th century (plot reproduced from Martin et al 2) has begun to reverse over the past decade. This concerning trend highlights the ...

Despite insufficient evidence to support direct-to-consumer genetic testing in routine clinical care, cardiovascular ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

P2Y 12 inhibitor‐based single antiplatelet therapy (SAPT) after drug‐eluting stent implantation reduces major bleeding without increasing the risk of major adverse cardiovascular and cerebral events ...

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, China. (Y.E.L., S.L., Litao Wang, Y.D., L. Wu, H.C., T ...

Low-density lipoprotein (LDL) is internalized into cells mainly through LDLR (LDL receptor)–mediated endocytosis. In an acidic endosome, LDLR is released from LDL and recycles back to the cell surface ...