The San Francisco 49ers preseason slate opens Saturday evening against the Denver Broncos at Levi's Stadium.

The first preseason game is in the books for the San Francisco 49ers. They suffer a defeat at home to the Denver Broncos 30-9. As expected, all of the 49ers' s ...

The 49ers opened their preseason with a 30-9 loss against the Denver Broncos from Levi's Stadium in Santa Clara, Calif. While ...

Jarrett Stidham threw two touchdown passes, leading the Denver Broncos to a 30-9 victory over the San Francisco 49ers ...

Kyle Shanhan revealed why standout 49ers rookie cornerback Upton Stout missed San Francisco's preseason opener against the ...

The 49ers just lost their preseason opener to the Denver Broncos by a score of 30-9. Here are the 49ers' grades for this ...

The 49ers scored a touchdown on their opening series of the preseason, then their defense crumbled by halftime against the ...

Stout, a rookie third-round pick, has logged an impressive start to training camp and even begun pushing for a potential starting role, per Noah Furtado of the San Francisco Chronicle, so it's ...

Nearly 40 players are brand new to the 49ers’ roster and poised to make their debut in Saturday’s preseason opener against ...

The last NFL preseason game to kick off tonight is the San Francisco 49ers vs. the Denver Broncos in this rivalry matchup.

The 49ers won't play their starters in their preseason debut against the Denver Broncos, but these 11 players will be worth ...