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  1. Sickle Cell Disease - Symptoms | NHLBI, NIH

    Aug 20, 2024 · Sickle Cell Disease Fact Sheet Learn basics about sickle cell disease, including symptoms, how to prevent health problems and treatment options.

  2. Sickle Cell Disease - What Is Sickle Cell Disease? | NHLBI, NIH

    Dec 10, 2025 · Sickle cell disease is a lifelong illness that may be managed through preventive screening and treatment strategies. Treatment reduces or helps manage symptoms and …

  3. How Sickle Cell Disease May Affect Your Health - NHLBI, NIH

    Aug 22, 2024 · Sickle cell disease can cause pain, infections, and joint problems throughout the body. It can also lead to severe anemia and complications in specific body parts.

  4. Sickle Cell Disease Fact Sheet - NHLBI, NIH

    Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. In this fact sheet, learn about the causes, signs and symptoms, diagnosis, and treatment of SCD.

  5. Sickle Cell Disease - Sickle Cell Trait | NHLBI, NIH

    Aug 22, 2024 · People with sickle cell trait carry only one copy of the sickle hemoglobin gene and rarely have any symptoms of sickle cell disease. However, in rare instances, some people who …

  6. Sickle Cell Disease - Causes and Risk Factors | NHLBI, NIH

    Aug 20, 2024 · Who can get sickle cell disease? Sickle cell disease is a genetic disorder caused by mutations in hemoglobin genes, leading to a faulty hemoglobin protein, called hemoglobin …

  7. SICKLE CELL DISEASE Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. People with SCD are born with it. This disease gets its name from the …

  8. Sickle Cell Disease - Treatment | NHLBI, NIH

    Sep 30, 2024 · Treatment options for sickle cell disease include medicines that lessen symptoms, blood transfusions, blood and bone marrow transplants, and gene therapy treatments. Bone …

  9. What is Sickle Cell Trait? Fact Sheet - NHLBI, NIH

    Mar 20, 2025 · Sickle cell trait occurs when a person has one copy of the sickle cell gene passed down from one parent, and a normal hemoglobin gene from the other parent. This fact sheet …

  10. Pregnancy, Reproduction, and Sickle Cell Disease - NHLBI, NIH

    Feb 4, 2025 · Sickle cell disease can affect sexual organs and other parts of the body in ways that affect quality of life and reproduction. Pregnancy puts extra stress on a woman’s body, raising …