Oprah Winfrey is one of the best-known, most-admired and successful people on the planet. After decades of public struggle with her weight, new medications and a new understanding of her body led to a breakthrough she describes in “Enough,” a book she co-wrote with Dr. Ania Jastreboff. Winfrey speaks with Jane Pauley about genetically influenced weight ranges, how they can be reset and why reframing weight as a medical issue — not a personal failure — changed everything. | CBS Sunday Morning