Dapsone gel (5% or 7.5%) is a prescription topical medication primarily used to treat acne vulgaris (both inflammatory and non-inflammatory acne) in adults and children 9 years and older. It works as a sulfone antibiotic to reduce acne-causing bacteria and lower inflammation. MedlinePlus (.gov) MedlinePlus (.gov) 2 Key Uses and Information Acne Treatment: It is highly effective for reducing acne pimples, often used once or twice daily. Off-Label Uses: In some cases, it may be used for other skin

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