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Scientists bring back dire wolves after 12,500 years of extinction. Colossal Biosciences has produced three dire wolf pups—two males and one female—using gene editing, cloning, and ancient DNA from fossils dated 13,000 to 72,000 years old. By editing 14 genes in gray wolf cells to match dire wolf traits like thick fur, stronger jaws, and broader skulls, scientists recreated the dire wolf phenotype. The embryos were implanted into domestic dogs. The pups, born in late 2024 and early 2025, now liv
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When your body makes new cells, it has to copy all your DNA perfectly—and that’s where DNA polymerase comes in. While other enzymes just set the stage (like helicase unzipping the DNA or primase laying down a starter), DNA polymerase does the actual building. It adds the correct DNA letters (nucleotides) one by one, creating an exact copy of your genetic code. But it’s not just a builder—it’s also a proofreader. If it makes a mistake, it can go back and fix it. No other enzyme in the replication
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